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REC8 anticorps (N-Term)

REC8 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783199
  • Antigène Voir toutes REC8 Anticorps
    REC8 (REC8 Homolog (Yeast) (REC8))
    Épitope
    • 16
    • 15
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 32
    • 31
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval
    Hôte
    • 57
    • 2
    Lapin
    Clonalité
    • 58
    • 1
    Polyclonal
    Conjugué
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp REC8 est non-conjugé
    Application
    • 52
    • 26
    • 26
    • 24
    • 14
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    QLQIGVIRVY SQQCQYLVED IQHILERLHR AQLQIRIDME TELPSLLLPN
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against REC8. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human REC8
    Top Product
    Discover our top product REC8 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 547 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    REC8 (REC8 Homolog (Yeast) (REC8))
    Autre désignation
    REC8 (REC8 Produits)
    Synonymes
    anticorps Rec8L1, anticorps mrec, anticorps HR21spB, anticorps REC8L1, anticorps Rec8p, anticorps REC8 meiotic recombination protein, anticorps REC8 homolog (yeast), anticorps REC8, anticorps Rec8
    Sujet
    REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
    Alias Symbols: HR21spB, MGC950, REC8L1, Rec8p
    Protein Interaction Partner: SYCP3, SMC3, SMC1A,
    Protein Size: 547
    Poids moléculaire
    62 kDa
    ID gène
    9985
    NCBI Accession
    NM_005132, NP_005123
    UniProt
    O95072
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