PRAS40 anticorps (C-Term)

N° du produit ABIN2783209

Détail du produit anti-PRAS40 anticorps

Antigène: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRAS40 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KSLPVSVPVW GFKEKRTEAR SSDEENGPPS SPDLDRIAAS MRALVLREAE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AKT1S1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 256 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRAS40

Antigène: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Autre désignation: AKT1S1 (AKT1S1 Produits)

Synonymes: anticorps MGC81452, anticorps lobe, anticorps pras40, anticorps fb34a04, anticorps wu:fb34a04, anticorps Lobe, anticorps PRAS40, anticorps 1110012J22Rik, anticorps AI227026, anticorps Lobel, anticorps AKT1 substrate 1 (proline rich) S homeolog, anticorps AKT1 substrate 1, anticorps AKT1 substrate 1 (proline rich), anticorps AKT1 substrate 1 (proline-rich), anticorps akt1s1.S, anticorps AKT1S1, anticorps akt1s1, anticorps Akt1s1

Sujet: AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Alias Symbols: Lobe, MGC2865, PRAS40
Protein Interaction Partner: MTOR, RPTOR, SGK1, RICTOR, MAPKAP1, MLST8, FAM114A1, YWHAQ, YWHAB, SQSTM1, RPS6KA5, TCEA2, YWHAG, EIF6, AKT2, AKT1,
Protein Size: 256

Poids moléculaire: 27 kDa

ID gène: 84335

NCBI Accession: NM_032375, NP_115751

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, L'effet Warburg