EIF4A1 anticorps (Middle Region)
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- Antigène Voir toutes EIF4A1 Anticorps
- EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Mouton, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF4A1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TMPSDVLEVT KKFMRDPIRI LVKKEELTLE GIRQFYINVE REEWKLDTLC
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 92%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against EIF4A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1
- Top Product
- Discover our top product EIF4A1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 406 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." dans: eLife, Vol. 6, (2017) (PubMed).
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Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." dans: eLife, Vol. 6, (2017) (PubMed).
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- Antigène
- EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
- Autre désignation
- EIF4A1 (EIF4A1 Produits)
- Synonymes
- anticorps DDX2A, anticorps EIF-4A, anticorps EIF4A, anticorps eIF-4A-I, anticorps eIF4A-I, anticorps BM-010, anticorps Ddx2a, anticorps Eif4, anticorps ddx2a, anticorps eif-4a, anticorps eif4a, anticorps eif4a1, anticorps fb49a04, anticorps im:7143023, anticorps wu:fb20a10, anticorps wu:fb49a04, anticorps wu:fc76a02, anticorps wu:fc96c01, anticorps wu:fd15g03, anticorps eukaryotic translation initiation factor 4A1, anticorps eukaryotic translation initiation factor 4A1 L homeolog, anticorps eukaryotic initiation factor 4A-I, anticorps eukaryotic translation initiation factor 4A1A, anticorps EIF4A1, anticorps Eif4a1, anticorps eif4a1.L, anticorps eif4a1, anticorps LOC695050, anticorps eif4a1a
- Sujet
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EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Alias Symbols: DDX2A, EIF-4A, EIF4A, eIF4A-I, eIF-4A-I
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, SH3RF2, TRAP1, FBXO6, ADRB2, CD81, NPM1, VCAM1, ITGA4, FN1, ESR1, LIG4, RPLP0P6, TMEM43, NDUFB11, ZBTB43, GPRC5A, EIF4G3, EIF4H, VDAC3, UQCRFS1, SDHA, RPS26, RPL19, RPL8, RPSA, ILF2, HSP90AB1, HSPA5, EIF4G2, EIF
Protein Size: 406 - Poids moléculaire
- 46 kDa
- ID gène
- 1973
- NCBI Accession
- NM_001416, NP_001407
- UniProt
- P60842
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