EIF4A1 anticorps (Middle Region)

N° du produit ABIN2783213

Détail du produit anti-EIF4A1 anticorps

Antigène: EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien, Saccharomyces cerevisiae, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TMPSDVLEVT KKFMRDPIRI LVKKEELTLE GIRQFYINVE REEWKLDTLC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 92%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EIF4A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EIF4A1 (ABIN2783213)

Tamarkin-Ben-Harush, Vasseur, Debart, Ulitsky, Dikstein: "Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." dans: eLife, Vol. 6, (2017) (PubMed).

Détails sur EIF4A1

Antigène: EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))

Autre désignation: EIF4A1 (EIF4A1 Produits)

Synonymes: anticorps DDX2A, anticorps EIF-4A, anticorps EIF4A, anticorps eIF-4A-I, anticorps eIF4A-I, anticorps BM-010, anticorps Ddx2a, anticorps Eif4, anticorps ddx2a, anticorps eif-4a, anticorps eif4a, anticorps eif4a1, anticorps fb49a04, anticorps im:7143023, anticorps wu:fb20a10, anticorps wu:fb49a04, anticorps wu:fc76a02, anticorps wu:fc96c01, anticorps wu:fd15g03, anticorps eukaryotic translation initiation factor 4A1, anticorps eukaryotic translation initiation factor 4A1 L homeolog, anticorps eukaryotic initiation factor 4A-I, anticorps eukaryotic translation initiation factor 4A1A, anticorps EIF4A1, anticorps Eif4a1, anticorps eif4a1.L, anticorps eif4a1, anticorps LOC695050, anticorps eif4a1a

Sujet: EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Alias Symbols: DDX2A, EIF-4A, EIF4A, eIF4A-I, eIF-4A-I
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, SH3RF2, TRAP1, FBXO6, ADRB2, CD81, NPM1, VCAM1, ITGA4, FN1, ESR1, LIG4, RPLP0P6, TMEM43, NDUFB11, ZBTB43, GPRC5A, EIF4G3, EIF4H, VDAC3, UQCRFS1, SDHA, RPS26, RPL19, RPL8, RPSA, ILF2, HSP90AB1, HSPA5, EIF4G2, EIF
Protein Size: 406

Poids moléculaire: 46 kDa

ID gène: 1973

NCBI Accession: NM_001416, NP_001407

UniProt: P60842