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EIF4A1 anticorps (Middle Region)

EIF4A1 Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Mouton, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783213
  • Antigène Voir toutes EIF4A1 Anticorps
    EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
    Épitope
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 30
    • 18
    • 17
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Rat, Souris, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Mouton, Saccharomyces cerevisiae
    Hôte
    • 27
    • 3
    Lapin
    Clonalité
    • 26
    • 4
    Polyclonal
    Conjugué
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EIF4A1 est non-conjugé
    Application
    • 23
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    TMPSDVLEVT KKFMRDPIRI LVKKEELTLE GIRQFYINVE REEWKLDTLC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 92%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against EIF4A1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1
    Top Product
    Discover our top product EIF4A1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 406 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tamarkin-Ben-Harush, Vasseur, Debart, Ulitsky, Dikstein: "Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress." dans: eLife, Vol. 6, (2017) (PubMed).

  • Antigène
    EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))
    Autre désignation
    EIF4A1 (EIF4A1 Produits)
    Synonymes
    anticorps DDX2A, anticorps EIF-4A, anticorps EIF4A, anticorps eIF-4A-I, anticorps eIF4A-I, anticorps BM-010, anticorps Ddx2a, anticorps Eif4, anticorps ddx2a, anticorps eif-4a, anticorps eif4a, anticorps eif4a1, anticorps fb49a04, anticorps im:7143023, anticorps wu:fb20a10, anticorps wu:fb49a04, anticorps wu:fc76a02, anticorps wu:fc96c01, anticorps wu:fd15g03, anticorps eukaryotic translation initiation factor 4A1, anticorps eukaryotic translation initiation factor 4A1 L homeolog, anticorps eukaryotic initiation factor 4A-I, anticorps eukaryotic translation initiation factor 4A1A, anticorps EIF4A1, anticorps Eif4a1, anticorps eif4a1.L, anticorps eif4a1, anticorps LOC695050, anticorps eif4a1a
    Sujet
    EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
    Alias Symbols: DDX2A, EIF-4A, EIF4A, eIF4A-I, eIF-4A-I
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, SH3RF2, TRAP1, FBXO6, ADRB2, CD81, NPM1, VCAM1, ITGA4, FN1, ESR1, LIG4, RPLP0P6, TMEM43, NDUFB11, ZBTB43, GPRC5A, EIF4G3, EIF4H, VDAC3, UQCRFS1, SDHA, RPS26, RPL19, RPL8, RPSA, ILF2, HSP90AB1, HSPA5, EIF4G2, EIF
    Protein Size: 406
    Poids moléculaire
    46 kDa
    ID gène
    1973
    NCBI Accession
    NM_001416, NP_001407
    UniProt
    P60842
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