Myosin 9 anticorps (Middle Region)

N° du produit ABIN2783216

Détail du produit anti-Myosin 9 anticorps

Antigène: Myosin 9 (MYH9)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin 9 est non-conjugé

Application: Western Blotting (WB)

Séquence: DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK

Homologie: Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MYH9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1960 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Myosin 9 (ABIN2783216)

Sabbir, Dillon, Mowat: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." dans: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).

Détails sur Myosin 9

Antigène: Myosin 9 (MYH9)

Autre désignation: MYH9 (MYH9 Produits)

Synonymes: anticorps BDPLT6, anticorps DFNA17, anticorps EPSTS, anticorps FTNS, anticorps MHA, anticorps NMHC-II-A, anticorps NMMHC-IIA, anticorps NMMHCA, anticorps C80049, anticorps D0Jmb2, anticorps E030044M24Rik, anticorps Fltn, anticorps Myhn-1, anticorps Myhn1, anticorps NMHC II-A, anticorps NMHCIIA, anticorps NMMHC II-a, anticorps NMMHC-A, anticorps TU72.6, anticorps fi22c04, anticorps myh9, anticorps myh9l2, anticorps wu:fi22c04, anticorps wu:fj85e11, anticorps zgc:162029, anticorps zgc:66164, anticorps NMMHC, anticorps myosin, anticorps non-muscle, anticorps nonmuscle, anticorps KLG/PTK7, anticorps dfna17, anticorps epsts, anticorps ftns, anticorps nmhc-ii-a, anticorps nmmhca, anticorps myosin heavy chain 9, anticorps myosin, heavy polypeptide 9, non-muscle, anticorps myosin, heavy chain 9a, non-muscle, anticorps myosin, heavy chain 9, non-muscle, anticorps myosin, heavy chain 9, non-muscle L homeolog, anticorps MYH9, anticorps Myh9, anticorps myh9a, anticorps myh9.L

Sujet: MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Alias Symbols: DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA, BDPLT6, NMMHC-IIA
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, SUMO3, IVNS1ABP, LGR4, MDM2, RPA3, RPA2, RPA1, EED, MYL6, MYH14, CDC73, OTUD6B, AKAP10, MYL12A, MYL9, TARDBP, FN1, UBD, PIK3C3, ACE, CSNK2A1, ACTB, PAN2, ITGA4, HSP90AB1, HSP90AA1, ESR1, CASP4, IQCB1, VCAM1, PPP2CA, Fcho2, TRAF3IP
Protein Size: 1960

Poids moléculaire: 226 kDa

ID gène: 4627

NCBI Accession: NM_002473, NP_002464

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex