CD36 anticorps (N-Term)

N° du produit ABIN2783229

Détail du produit anti-CD36 anticorps

Antigène: CD36

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Chien, Cheval, Lapin, Boeuf (Vache), Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD36 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KTIKKQVVLE EGTIAFKNWV KTGTEVYRQF WIFDVQNPQE VMMNSSNIQV

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD36. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CD36

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 472 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD36

Antigène: CD36

Autre désignation: CD36 (CD36 Produits)

Synonymes: anticorps BDPLT10, anticorps CHDS7, anticorps FAT, anticorps GP3B, anticorps GP4, anticorps GPIV, anticorps PASIV, anticorps SCARB3, anticorps Fat, anticorps Scarb3, anticorps GPIIIB, anticorps PAS-4, anticorps zgc:92513, anticorps CD36 molecule, anticorps CD36 molecule (thrombospondin receptor), anticorps CD36, anticorps Cd36, anticorps cd36

Sujet: CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency. The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, BDPLT10
Protein Interaction Partner: CHRD, APP, CAND1, ITGA2B, MATK, SRC, THBS1, ITGB3, LYN, YES1, ITGA6, CD9, FYN, ITGB1, COL1A2, COL1A1, VLDLR, LDLR, HSD11B1,
Protein Size: 472

Poids moléculaire: 53 kDa

ID gène: 948

NCBI Accession: NM_001001547, NP_001001547

UniProt: P16671

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins