TPI1 anticorps (N-Term)

N° du produit ABIN2783242

Détail du produit anti-TPI1 anticorps

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Épitope: N-Term

Reactivité: Humain, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPI1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TPI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TPI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 249 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TPI1 (ABIN2783242)

Ralser, Nebel, Kleindorp, Krobitsch, Lehrach, Schreiber, Reinhardt, Timmermann: "Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans." dans: BMC genetics, Vol. 9, pp. 38, (2008) (PubMed).

Détails sur TPI1

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Autre désignation: TPI1 (TPI1 Produits)

Synonymes: anticorps TIM, anticorps TPI, anticorps TIM1, anticorps hTIM, anticorps tpi, anticorps tpi1, anticorps TPI1, anticorps AI255506, anticorps Tpi, anticorps Tpi-1, anticorps GB17473, anticorps Tim, anticorps CG2171, anticorps Dmel\\CG2171, anticorps ND14, anticorps TPIS, anticorps sgk, anticorps wstd, anticorps DrTPI-A, anticorps DrTPI-B, anticorps TIM-B, anticorps cb179, anticorps wu:fb51c02, anticorps triosephosphate isomerase 1, anticorps timeless circadian regulator, anticorps triosephosphate isomerase 1 S homeolog, anticorps triosephosphate isomerase, anticorps triose-phosphate isomerase, anticorps Triose-phosphate isomerase, anticorps triose-phosphate isomerase, putative, anticorps timeless circadian clock, anticorps Triose phosphate isomerase, anticorps Triosephosphate isomerase, anticorps triosephosphate isomerase 1a, anticorps triosephosphate isomerase 1b, anticorps TPI1, anticorps TIMELESS, anticorps tpi1, anticorps Tpi1, anticorps tpi1.S, anticorps Tpi, anticorps tpiA, anticorps CNE05000, anticorps Fnod_0738, anticorps Tlet_0996, anticorps SARE_RS16215, anticorps PKH_126640, anticorps Timeless, anticorps tpi-1, anticorps tpi1a, anticorps tpi1b

Sujet: TPI1 belongs to the triosephosphate isomerase family. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
Alias Symbols: MGC88108, TPI, TIM
Protein Interaction Partner: MDM2, UBC, RNF2, EZH2, SUZ12, TARDBP, YWHAQ, SP1, UBD, HCVgp1, IQCB1, ATF2, LIG4, SSU72, SEC23IP, PDIA6, PRDX6, VCL, UBA52, TKT, PGK1, MPST, GPI, GAPDH, ENO1, APP, CUL1, CDK2, TERF1, POT1, PSMA3, MAPK6, PCNA, HDAC5, UCHL5, EGFR, LIPT1, SETDB1, DDX24, CFL1
Protein Size: 249

Poids moléculaire: 27 kDa

ID gène: 7167

NCBI Accession: NM_000365, NP_000356

UniProt: P60174

Pathways: Cell RedoxHomeostasis