UMPS anticorps (C-Term)

N° du produit ABIN2783243

Détail du produit anti-UMPS anticorps

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Cheval, Chien, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UMPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 75%

Attributs du produit: This is a rabbit polyclonal antibody against UMPS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 480 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UMPS (ABIN2783243)

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." dans: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Détails sur UMPS

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Autre désignation: UMPS (UMPS Produits)

Synonymes: anticorps zgc:55702, anticorps zgc:55723, anticorps UMPS, anticorps OPRT, anticorps 1700095D23Rik, anticorps AA408257, anticorps AL033308, anticorps BB164745, anticorps Orotidine 5'-phosphate decarboxylase, anticorps uridine monophosphate synthetase, anticorps uridine monophosphate synthetase L homeolog, anticorps uridine 5'-monophosphate synthase, anticorps umps-1, anticorps umps, anticorps umps.L, anticorps UMPS, anticorps LOC100556619, anticorps Umps

Sujet: OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.
Alias Symbols: OPRT
Protein Interaction Partner: UBC, CALU, PLA2G12A, ZNF227, RPS29, PAXIP1, PSEN1, NOS3, APRT, A2M, CUL3, USP50, CDC42EP3, DLST,
Protein Size: 480

Poids moléculaire: 52 kDa

ID gène: 7372

NCBI Accession: NM_000373, NP_000364

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process