AKR1B1 anticorps (N-Term)

N° du produit ABIN2783262

Détail du produit anti-AKR1B1 anticorps

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ASRLLLNNGA KMPILGLGTW KSPPGQVTEA VKVAIDVGYR HIDCAHVYQN

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 86%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 316 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1B1

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Autre désignation: AKR1B1 (AKR1B1 Produits)

Synonymes: anticorps ADR, anticorps ALDR1, anticorps ALR2, anticorps AR, anticorps ALDRED, anticorps ALR-P-I, anticorps Akr1b3, anticorps Akr1b4, anticorps Aldr1, anticorps Alr, anticorps RATALDRED, anticorps akr1b7, anticorps zgc:86611, anticorps aldo-keto reductase family 1 member B, anticorps aldo-keto reductase family 1, member B1 (aldose reductase), anticorps aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog, anticorps AKR1B1, anticorps Akr1b1, anticorps akr1b1.S, anticorps akr1b1

Sujet: AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADR, ALDR1, ALR2, AR, MGC1804
Protein Interaction Partner: UBC, ASB18, ASB9, ASB5, SMAD1, SORD, SHBG, TFE3,
Protein Size: 316

Poids moléculaire: 36 kDa

ID gène: 231

NCBI Accession: NM_001628, NP_001619

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process