APEH anticorps (N-Term)

N° du produit ABIN2783264

Détail du produit anti-APEH anticorps

Antigène: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APEH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VYEDDCFGCL SWSHSETHLL YVAEKKRPKA ESFFQTKALD VSASDDEIAR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against APEH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human APEH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 732 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APEH

Antigène: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Autre désignation: APEH (APEH Produits)

Synonymes: anticorps AARE, anticorps ACPH, anticorps APH, anticorps D3F15S2, anticorps D3S48E, anticorps DNF15S2, anticorps OPH, anticorps AAP, anticorps cb5, anticorps sb:cb5, anticorps wu:fi37d02, anticorps acylaminoacyl-peptide hydrolase, anticorps acylpeptide hydrolase, anticorps APEH, anticorps Apeh, anticorps apeh

Sujet: APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
Protein Interaction Partner: IST1, UBC, LGALS8, APEH, SNX6, CAND1, TOLLIP, CYHR1, JMJD6, HSPA4L, IPO7, DNM1L, VPS26A, NMI, H1FX, ZYX, TBCD, TARS, STAT1, SHMT2, SHMT1, PPM1G, SERPINE2, PAWR, LAMP2, KARS, HIST1H1C, GARS, CTTN, CARS, PREPL, SHBG, UBA5, TMEM62,
Protein Size: 732

Poids moléculaire: 81 kDa

ID gène: 327

NCBI Accession: NM_001640, NP_001631

UniProt: P13798