APEH anticorps (Middle Region)
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- Antigène Voir toutes APEH Anticorps
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Cobaye, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APEH est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against APEH. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human APEH
- Top Product
- Discover our top product APEH Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 732 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
- Autre désignation
- APEH (APEH Produits)
- Synonymes
- anticorps AARE, anticorps ACPH, anticorps APH, anticorps D3F15S2, anticorps D3S48E, anticorps DNF15S2, anticorps OPH, anticorps AAP, anticorps cb5, anticorps sb:cb5, anticorps wu:fi37d02, anticorps acylaminoacyl-peptide hydrolase, anticorps acylpeptide hydrolase, anticorps APEH, anticorps Apeh, anticorps apeh
- Sujet
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APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Alias Symbols: ACPH, APH, D3F15S2, D3S48E, DNF15S2, MGC2178, OPH, AARE
Protein Interaction Partner: IST1, UBC, LGALS8, APEH, SNX6, CAND1, TOLLIP, CYHR1, JMJD6, HSPA4L, IPO7, DNM1L, VPS26A, NMI, H1FX, ZYX, TBCD, TARS, STAT1, SHMT2, SHMT1, PPM1G, SERPINE2, PAWR, LAMP2, KARS, HIST1H1C, GARS, CTTN, CARS, PREPL, SHBG, UBA5, TMEM62,
Protein Size: 732 - Poids moléculaire
- 81 kDa
- ID gène
- 327
- NCBI Accession
- NM_001640, NP_001631
- UniProt
- P13798
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