TCAP anticorps (N-Term)

N° du produit ABIN2783290

Détail du produit anti-TCAP anticorps

Antigène: TCAP (Titin-Cap (Telethonin) (TCAP))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCAP est non-conjugé

Application: Western Blotting (WB)

Séquence: CSLHEEDTQR HETYHQQGQC QVLVQRSPWL MMRMGILGRG LQEYQLPYQR

Homologie: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TCAP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 167 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCAP

Antigène: TCAP (Titin-Cap (Telethonin) (TCAP))

Autre désignation: TCAP (TCAP Produits)

Synonymes: anticorps TCAP, anticorps CMD1N, anticorps LGMD2G, anticorps T-cap, anticorps TELE, anticorps telethonin, anticorps AI503981, anticorps AJ223855, anticorps titin-cap, anticorps titin-cap (telethonin), anticorps titin-cap S homeolog, anticorps TCAP, anticorps tcap, anticorps tcap.S, anticorps Tcap

Sujet: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1N, LGMD2G, T-cap, TELE, telethonin
Protein Interaction Partner: TRIM63, TRIM55, RELA, FYN, FAS, ATXN1, MDM2, TTN, PDPK1, MYOZ3, ANKRD2, MYOZ1, MSTN, MYOZ2,
Protein Size: 167

Poids moléculaire: 19 kDa

ID gène: 8557

NCBI Accession: NM_003673, NP_003664

UniProt: O15273