Sep 15 anticorps (Middle Region)

N° du produit ABIN2783300

Détail du produit anti-Sep 15 anticorps

Antigène: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Porc, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sep 15 est non-conjugé

Application: Western Blotting (WB)

Séquence: SDKPKLFRGL QIKYVRGSDP VLKLLDDNGN IAEELSILKW NTDSVEEFLS

Homologie: Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SEP15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SEP15

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 165 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sep 15

Antigène: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Autre désignation: SEP15 (SEP15 Produits)

Synonymes: anticorps 9430015P09Rik, anticorps cb29, anticorps zgc:86882, anticorps BcDNA:SD16138, anticorps Dmel\\CG7484, anticorps Prise 8, anticorps Sep15, anticorps selenoprotein F, anticorps CG7484 gene product from transcript CG7484-RB, anticorps SELENOF, anticorps Selenof, anticorps selenof, anticorps CG7484

Sujet: SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: METTL23, UBC, DCUN1D1, CUL3, BAMBI, XRCC6, UGGT2, UGGT1,
Protein Size: 165

Poids moléculaire: 15 kDa

ID gène: 9403

NCBI Accession: NM_004261, NP_004252

UniProt: O60613