Prohibitin 2 anticorps (C-Term)
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- Antigène Voir toutes Prohibitin 2 (PHB2) Anticorps
- Prohibitin 2 (PHB2)
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Prohibitin 2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PHB2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PHB2
- Top Product
- Discover our top product PHB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 299 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Prohibitin 2 (PHB2)
- Autre désignation
- PHB2 (PHB2 Produits)
- Sujet
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PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Protein Interaction Partner: HUWE1, IGF1R, HDAC1, ESR1, KIAA1244, NCOR1, SUMO2, STAU1, UBC, MDM2, ASB14, ASB17, SUZ12, EED, RNF2, UPF2, ADRB2, CDK2, env, VCAM1, TEAD3, ITGA4, ILF3, FN1, ATF2, C1QBP, AFP, UBL4A, EPAS1, FMNL1, PAXIP1, MDC1, MYOD1, MEF2A, FHL2, ECT2, BRCA1, AKT1, Htt, U
Protein Size: 299 - Poids moléculaire
- 33 kDa
- ID gène
- 11331
- NCBI Accession
- NM_007273, NP_009204
- UniProt
- Q99623
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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