GSTA3 anticorps (Middle Region)
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- Antigène Voir toutes GSTA3 Anticorps
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GSTA3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR
- Homologie
- Human: 100%, Mouse: 79%, Sheep: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against GSTA3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human GSTA3
- Top Product
- Discover our top product GSTA3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 222 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
- Autre désignation
- GSTA3 (GSTA3 Produits)
- Synonymes
- anticorps GSTA3, anticorps GST, anticorps GSTA1, anticorps GSTA3-3, anticorps GTA3, anticorps GSTA2, anticorps Gst2-3, anticorps Yc2, anticorps glutathione S-transferase alpha 3, anticorps glutathione S-transferase A2, anticorps glutathione S-transferase, anticorps glutathione S-transferase, alpha 3, anticorps glutathione S-transferase Yc, anticorps GSTA3, anticorps LOC474938, anticorps gsta3, anticorps Gsta3, anticorps LOC100328911
- Sujet
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Interaction Partner: BAG3, APP,
Protein Size: 222 - Poids moléculaire
- 25 kDa
- ID gène
- 2940
- NCBI Accession
- NM_000847, NP_000838
- UniProt
- Q16772
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