GATM anticorps (Middle Region)

N° du produit ABIN2783416

Détail du produit anti-GATM anticorps

Antigène: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATM est non-conjugé

Application: Western Blotting (WB)

Séquence: PCFDAADFIR AGRDIFAQRS QVTNYLGIEW MRRHLAPDYR VHIISFKDPN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against GATM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GATM

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 423 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GATM

Antigène: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Autre désignation: GATM (GATM Produits)

Synonymes: anticorps AT, anticorps AGAT, anticorps CCDS3, anticorps 1810003P21Rik, anticorps AI314789, anticorps cb409, anticorps wu:fa08a06, anticorps zgc:65855, anticorps glycine amidinotransferase (L-arginine:glycine amidinotransferase) L homeolog, anticorps glycine amidinotransferase, anticorps glycine amidinotransferase (L-arginine:glycine amidinotransferase), anticorps gatm.L, anticorps GATM, anticorps Gatm, anticorps gatm

Sujet: GATM is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AGAT, AT
Protein Interaction Partner: CYP2E1, Gatm,
Protein Size: 423

Poids moléculaire: 44 kDa

ID gène: 2628

NCBI Accession: NM_001482, NP_001473

UniProt: P50440