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POLR3B anticorps (C-Term)

POLR3B Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Saccharomyces cerevisiae, Chévre WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783516
  • Antigène Voir toutes POLR3B Anticorps
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Épitope
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 27
    • 27
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Saccharomyces cerevisiae, Chévre
    Hôte
    • 37
    • 2
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLR3B est non-conjugé
    Application
    • 27
    • 24
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    IEKVMISSNA EDAFLIKMLL RQTRRPEIGD KFSSRHGQKG VCGLIVPQED
    Homologie
    Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against POLR3B. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human POLR3B
    Top Product
    Discover our top product POLR3B Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1133 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yee, Gong, Huang, Lorent, Dolan, Maraia, Pack: "Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development." dans: PLoS biology, Vol. 5, Issue 11, pp. e312, (2007) (PubMed).

  • Antigène
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Autre désignation
    POLR3B (POLR3B Produits)
    Synonymes
    anticorps RGD1565311, anticorps C128, anticorps HLD8, anticorps RPC2, anticorps 2700078H01Rik, anticorps A330032P03Rik, anticorps C85372, anticorps RNA polymerase III subunit B, anticorps polymerase (RNA) III (DNA directed) polypeptide B, anticorps Polr3b, anticorps POLR3B
    Sujet
    POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
    Alias Symbols: FLJ10388, RPC2, C128, HLD8
    Protein Interaction Partner: SUMO2, UBC, POLR3H, TSR1, POLR1D, CRCP, POLR3A, POLR1C, POLR2H, POLR3D, RPAP2, RPAP1, GPN1, RAE1,
    Protein Size: 1133
    Poids moléculaire
    128 kDa
    ID gène
    55703
    NCBI Accession
    NM_018082, NP_060552
    UniProt
    Q9NW08
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