LTC4S anticorps (N-Term)

N° du produit ABIN2783616

Détail du produit anti-LTC4S anticorps

Antigène: LTC4S (Leukotriene C4 Synthase (LTC4S))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Rat, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LTC4S est non-conjugé

Application: Western Blotting (WB)

Séquence: MKDEVALLAA VTLLGVLLQA YFSLQVISAR RAFRVSPPLT TGPPEFERVY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against LTC4S. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LTC4S

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 150 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LTC4S (ABIN2783616)

Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." dans: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, (2015) (PubMed).

Détails sur LTC4S

Antigène: LTC4S (Leukotriene C4 Synthase (LTC4S))

Autre désignation: LTC4S (leukotriene C4 synthase) (LTC4S) (LTC4S Produits)

Synonymes: anticorps LTC4S, anticorps ltc4s, anticorps si:dkey-33h4.2, anticorps leukotriene C4 synthase, anticorps leukotriene C4 synthase-like, anticorps leukotriene C4 synthase, gene 1, anticorps Ltc4s, anticorps LTC4S, anticorps LTC4SL, anticorps ltc4s.1, anticorps ltc4s

Sujet: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC33147
Protein Interaction Partner: MGST1, LTC4S, ALOX5AP, ALOX5,
Protein Size: 150

Poids moléculaire: 16 kDa

ID gène: 4056

NCBI Accession: NM_145867, NP_665874

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin