PCDHAC1 anticorps (N-Term)
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- Antigène Voir toutes PCDHAC1 Anticorps
- PCDHAC1 (Protocadherin alpha Subfamily C, 1 (PCDHAC1))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCDHAC1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RVQALDPDEG SNGEVQYSLS NSTQAELRHR FHVHPKSGEV QVAASLGPPE
- Homologie
- Cow: 90%, Dog: 90%, Guinea Pig: 92%, Horse: 90%, Human: 100%, Mouse: 100%, Rabbit: 90%, Rat: 100%, Zebrafish: 90%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCDHAC1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHAC1
- Top Product
- Discover our top product PCDHAC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 818 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PCDHAC1 (Protocadherin alpha Subfamily C, 1 (PCDHAC1))
- Autre désignation
- PCDHAC1 (PCDHAC1 Produits)
- Synonymes
- anticorps PCDH-ALPHA-C1, anticorps CNRc1, anticorps rCNRvc1, anticorps protocadherin alpha subfamily C, 1, anticorps PCDHAC1, anticorps Pcdhac1
- Sujet
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PCDHAC1 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: PCDH-ALPHA-C1
Protein Size: 818 - Poids moléculaire
- 87 kDa
- ID gène
- 56135
- NCBI Accession
- NM_031882, NP_114088
- UniProt
- B2RNA7
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