PCDHA5 anticorps (N-Term)
-
- Antigène Voir toutes PCDHA5 Anticorps
- PCDHA5 (Protocadherin alpha 5 (PCDHA5))
-
Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PCDHA5 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- VYSRRGSLGS RLLLLWLLLA YWKAGSGQLH YSIPEEAKHG TFVGRIAQDL
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCDHA5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA5
- Top Product
- Discover our top product PCDHA5 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 936 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PCDHA5 (Protocadherin alpha 5 (PCDHA5))
- Autre désignation
- PCDHA5 (PCDHA5 Produits)
- Synonymes
- anticorps CNR6, anticorps CNRN6, anticorps CNRS6, anticorps CRNR6, anticorps PCDH-ALPHA5, anticorps Cnr6, anticorps Crnr6, anticorps rCNRv05, anticorps PCDHA5, anticorps Pcdha5, anticorps protocadherin alpha 5, anticorps protocadherin alpha-5, anticorps PCDHA5, anticorps Pcdha5, anticorps LOC100738784, anticorps LOC100847156, anticorps LOC100713870, anticorps LOC100629824
- Sujet
-
The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Protein Size: 936 - Poids moléculaire
- 99 kDa
- ID gène
- 56143
- NCBI Accession
- NM_018908, NP_061731
- UniProt
- Q9Y5H7
-