NDFIP2 anticorps (Middle Region)

N° du produit ABIN2783749

Détail du produit anti-NDFIP2 anticorps

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Rat, Poisson zèbre (Danio rerio), Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDFIP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NDFIP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NDFIP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 336 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NDFIP2

Antigène: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Autre désignation: NDFIP2 (NDFIP2 Produits)

Synonymes: anticorps MGC68708, anticorps DKFZp459H0627, anticorps N4WBP5A, anticorps 0710001O20Rik, anticorps 2810436B12Rik, anticorps 9130207N19Rik, anticorps N4wbp5a, anticorps mKIAA1165, anticorps Nedd4 family interacting protein 2 S homeolog, anticorps Nedd4 family interacting protein 2, anticorps ndfip2.S, anticorps NDFIP2, anticorps ndfip2, anticorps Ndfip2

Sujet: NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: UBC, NEDD4L, NEDD4, ELAVL1, ITCH, WWP2, SRC, PTEN, LYN, FYN, EGFR, SMURF1, SLC11A2,
Protein Size: 336

Poids moléculaire: 36 kDa

ID gène: 54602

NCBI Accession: NM_019080, NP_061953

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome