Junctophilin 3 anticorps (N-Term)

N° du produit ABIN2783795

Détail du produit anti-Junctophilin 3 anticorps

Antigène: Junctophilin 3 (JPH3)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Junctophilin 3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SSGGRFNFDD GGSYCGGWED GKAHGHGVCT GPKGQGEYTG SWSHGFEVLG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against JPH3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human JPH3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 748 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Junctophilin 3

Antigène: Junctophilin 3 (JPH3)

Autre désignation: JPH3 (JPH3 Produits)

Synonymes: anticorps CAGL237, anticorps HDL2, anticorps JP-3, anticorps JP3, anticorps TNRC22, anticorps Jp3, anticorps fc26e06, anticorps si:ch211-255l14.9, anticorps wu:fc26e06, anticorps junctophilin 3, anticorps JPH3, anticorps Jph3, anticorps jph3

Sujet: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAGL237, FLJ44707, HDL2, JP-3, JP3, TNRC22
Protein Interaction Partner: PPP1CA, SMAD3, BGN, STK24,
Protein Size: 748

Poids moléculaire: 81 kDa

ID gène: 57338

NCBI Accession: NM_020655, NP_065706

UniProt: Q8WXH2