SRPRB anticorps (C-Term)

N° du produit ABIN2783831

Détail du produit anti-SRPRB anticorps

Antigène: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRPRB est non-conjugé

Application: Western Blotting (WB)

Séquence: APAQLGKKGK EFEFSQLPLK VEFLECSAKG GRGDVGSADI QDLEKWLAKI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SRPRB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SRPRB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 271 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SRPRB (ABIN2783831)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur SRPRB

Antigène: SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))

Autre désignation: SRPRB (SRPRB Produits)

Synonymes: anticorps wu:fk57h10, anticorps zgc:111820, anticorps zgc:92746, anticorps apmcf1, anticorps APMCF1, anticorps AA409543, anticorps Ab2-417, anticorps Ba1-667, anticorps Cc1-8, anticorps signal recognition particle receptor, B subunit, anticorps SRP receptor beta subunit S homeolog, anticorps SRP receptor beta subunit, anticorps SRPRB, anticorps srprb, anticorps srprb.S, anticorps Srprb

Sujet: SRPRB has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Alias Symbols: APMCF1
Protein Interaction Partner: ERLIN2, UBC, STAU1, MDM2, FBXO6, PPP6R1, ADRB2, LMNA, UBL4A, CA9, UBE2L3, TAGLN, SPR, SNRPC, S100A10, RRBP1, RPL38, RFX5, RBMS1, PIN4, PFN1, ACAA1, TMED4, TMEM65, RPS10P5, MRRF, SARNP, NABP2, MRPL14, TMBIM1, SUGP1, SBDS, MRPS28, TARDBP, TOMM40, UBE4B, SF3
Protein Size: 271

Poids moléculaire: 30 kDa

ID gène: 58477

NCBI Accession: NM_021203, NP_067026

UniProt: Q9Y5M8

Pathways: ER-Nucleus Signaling