ADAM19 anticorps (N-Term)

N° du produit ABIN2783899

Détail du produit anti-ADAM19 anticorps

Antigène: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM19 est non-conjugé

Application: Western Blotting (WB)

Séquence: VADYLEFQKN RRDQDATKHK LIEIANYVDK FYRSLNIRIA LVGLEVWTHG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ADAM19. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM19

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 956 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ADAM19 (ABIN2783899)

Marballi, Cruz, Thompson, Walss-Bass: "Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36431, (2012) (PubMed).

Détails sur ADAM19

Antigène: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Autre désignation: ADAM19 (Adam19 Produits)

Synonymes: anticorps AL024287, anticorps M[b], anticorps Mltnb, anticorps MADDAM, anticorps MLTNB, anticorps Sox30, anticorps fksg34, anticorps maddam, anticorps mltnb, anticorps a disintegrin and metallopeptidase domain 19 (meltrin beta), anticorps ADAM metallopeptidase domain 19, anticorps ADAM metallopeptidase domain 19 S homeolog, anticorps Adam19, anticorps ADAM19, anticorps adam19.S

Sujet: ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.
Alias Symbols: FKSG34, MADDAM, MLTNB
Protein Interaction Partner: UBC, TNFSF11, COPB1, NRG1, FURIN, A2M, ABI2, SH3GL2, ESF1,
Protein Size: 956

Poids moléculaire: 82 kDa

ID gène: 8728

NCBI Accession: NM_023038, NP_075525

UniProt: Q9H013