MANEA anticorps (Middle Region)

N° du produit ABIN2783932

Détail du produit anti-MANEA anticorps

Antigène: MANEA (Mannosidase, Endo-alpha (MANEA))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MANEA est non-conjugé

Application: Western Blotting (WB)

Séquence: KVTFHIEPYS NRDDQNMYKN VKYIIDKYGN HPAFYRYKTK TGNALPMFYV

Homologie: Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 92%, Rat: 100%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against MANEA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MANEA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 462 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MANEA

Antigène: MANEA (Mannosidase, Endo-alpha (MANEA))

Autre désignation: MANEA (MANEA Produits)

Synonymes: anticorps ENDO, anticorps hEndo, anticorps Enman, anticorps 4932703L02Rik, anticorps fi29h09, anticorps zgc:92825, anticorps wu:fi29h09, anticorps mannosidase endo-alpha, anticorps mannosidase, endo-alpha, anticorps MANEA, anticorps Manea, anticorps manea

Sujet: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
Alias Symbols: DKFZp686D20120, FLJ12838, hEndo, ENDO
Protein Interaction Partner: UBC, DNM2, PRD, AMPH,
Protein Size: 462

Poids moléculaire: 54 kDa

ID gène: 79694

NCBI Accession: NM_024641, NP_078917

UniProt: Q5SRI9