PCDHA3 anticorps (N-Term)
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- Antigène Voir toutes PCDHA3 Anticorps
- PCDHA3 (Protocadherin alpha 3 (PCDHA3))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Cheval, Boeuf (Vache), Cobaye, Rat, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCDHA3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LFSWREDPGA QCLLLSLLLL AASEVGSGQL HYSVSEEAKH GTFVGRIAQD
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCDHA3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA3
- Top Product
- Discover our top product PCDHA3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 950 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PCDHA3 (Protocadherin alpha 3 (PCDHA3))
- Autre désignation
- PCDHA3 (PCDHA3 Produits)
- Synonymes
- anticorps PCDH-ALPHA3, anticorps mKIAA0345, anticorps PCDHA2, anticorps PCDHA3, anticorps PCDHA4, anticorps Pcdha3, anticorps protocadherin alpha 3, anticorps protocadherin alpha-3, anticorps PCDHA3, anticorps Pcdha3, anticorps pcdha3, anticorps LOC100713314
- Sujet
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PCDHA3 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: MGC141669, PCDH-ALPHA3
Protein Size: 950 - Poids moléculaire
- 99 kDa
- ID gène
- 56145
- NCBI Accession
- NM_018906, NP_061729
- UniProt
- Q9Y5H8
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