PCDHA6 anticorps (C-Term)
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- Antigène Voir toutes PCDHA6 Anticorps
- PCDHA6 (Protocadherin alpha 6 (PCDHA6))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCDHA6 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LVKDHGEPAL TATATVLVSL VESGQAPKAS SRASVGAAGP EAALVDVNVY
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCDHA6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA6
- Top Product
- Discover our top product PCDHA6 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 803 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PCDHA6 (Protocadherin alpha 6 (PCDHA6))
- Autre désignation
- PCDHA6 (PCDHA6 Produits)
- Synonymes
- anticorps CNR2, anticorps CNRN2, anticorps CNRS2, anticorps CRNR2, anticorps PCDH-ALPHA6, anticorps CNR, anticorps Cnr2, anticorps Crnr2, anticorps rCNRv06, anticorps PCDHA3, anticorps PCDHA6, anticorps PCDHA7, anticorps PCDHA9, anticorps protocadherin alpha 6, anticorps PCDHA6, anticorps Pcdha6
- Sujet
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PCDHA6 contains 6 cadherin domains. It is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6
Protein Interaction Partner: CUL3, UBC, RELN,
Protein Size: 803 - Poids moléculaire
- 84 kDa
- ID gène
- 56142
- NCBI Accession
- NM_031848, NP_114036
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