Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

DISP1 anticorps (Middle Region)

DISP1 Reactivité: Humain, Souris, Rat, Cheval, Lapin, Poisson zèbre (Danio rerio), Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784069
  • Antigène Voir toutes DISP1 Anticorps
    DISP1 (Dispatched Homolog 1 (DISP1))
    Épitope
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Cheval, Lapin, Poisson zèbre (Danio rerio), Porc
    Hôte
    • 5
    • 1
    Lapin
    Clonalité
    • 6
    Polyclonal
    Conjugué
    • 6
    Cet anticorp DISP1 est non-conjugé
    Application
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    FVLCDVWNYT KFDKPHAETS ETVSITLQHA ALSMFVTSFT TAAAFYANYV
    Homologie
    Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against DISP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human DISP1
    Top Product
    Discover our top product DISP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1524 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DISP1 (Dispatched Homolog 1 (DISP1))
    Autre désignation
    DISP1 (DISP1 Produits)
    Synonymes
    anticorps DISP1, anticorps DISPA, anticorps 1190008H24Rik, anticorps DispA, anticorps con, anticorps zgc:111866, anticorps dispatched, anticorps dispatched RND transporter family member 1, anticorps dispatched homolog 1 (Drosophila), anticorps CpipJ_CPIJ008642, anticorps DISP1, anticorps Disp1, anticorps disp1
    Sujet
    DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
    Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
    Protein Interaction Partner: LAPTM5, UBC,
    Protein Size: 1524
    Poids moléculaire
    171 kDa
    ID gène
    84976
    NCBI Accession
    NM_032890, NP_116279
    UniProt
    Q96F81
    Pathways
    Signalisation Hedgehog
Vous êtes ici:
Support technique