PCDH15 anticorps (N-Term)

N° du produit ABIN2784074

Détail du produit anti-PCDH15 anticorps

Antigène: PCDH15 (Protocadherin-15 (PCDH15))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDH15 est non-conjugé

Application: Western Blotting (WB)

Séquence: HSIVVQVQCI NKKVGTIIYH EVRIVVRDRN DNSPTFKHES YYATVNELTP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCDH15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDH15

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 719 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDH15

Antigène: PCDH15 (Protocadherin-15 (PCDH15))

Autre désignation: PCDH15 (PCDH15 Produits)

Synonymes: anticorps CDHR15, anticorps DFNB23, anticorps USH1F, anticorps BB078305, anticorps ENSMUSG00000046980, anticorps Gm9815, anticorps Ush1f, anticorps av, anticorps nmf19, anticorps protocadherin-15, anticorps protocadherin related 15, anticorps protocadherin-15, anticorps protocadherin 15, anticorps PCDH15, anticorps CpipJ_CPIJ005081, anticorps Pcdh15

Sujet: PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Protein Interaction Partner: Dlg4,
Protein Size: 719

Poids moléculaire: 80 kDa

ID gène: 65217

NCBI Accession: NM_001142763

UniProt: A2A3E5

Pathways: Sensory Perception of Sound