RFT1 anticorps (N-Term)

N° du produit ABIN2784093

Détail du produit anti-RFT1 anticorps

Antigène: RFT1 (RFT1 Homolog (RFT1))

Épitope: N-Term

Reactivité: Humain, Chien, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFT1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 541 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RFT1

Antigène: RFT1 (RFT1 Homolog (RFT1))

Autre désignation: RFT1 (RFT1 Produits)

Synonymes: anticorps GB14370, anticorps CDG1N, anticorps D930025H04, anticorps RGD1562654, anticorps protein RFT1 homolog, anticorps RFT1 homolog, anticorps LOC412489, anticorps LOC100453537, anticorps RFT1, anticorps rft1, anticorps LOC100633251, anticorps LOC100651701, anticorps Rft1

Sujet: N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
Alias Symbols: CDG1N
Protein Interaction Partner: PSMA3, UBC, NEDD4,
Protein Size: 541

Poids moléculaire: 60 kDa

ID gène: 91869

NCBI Accession: NM_052859, NP_443091

UniProt: Q96AA3