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RFT1 anticorps (N-Term)

RFT1 Reactivité: Humain, Chien, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784093
  • Antigène Voir toutes RFT1 Anticorps
    RFT1 (RFT1 Homolog (RFT1))
    Épitope
    • 8
    • 8
    • 7
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Chien, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Rat
    Hôte
    • 17
    • 1
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RFT1 est non-conjugé
    Application
    • 17
    • 14
    • 13
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV
    Homologie
    Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1
    Top Product
    Discover our top product RFT1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 541 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RFT1 (RFT1 Homolog (RFT1))
    Autre désignation
    RFT1 (RFT1 Produits)
    Synonymes
    anticorps GB14370, anticorps CDG1N, anticorps D930025H04, anticorps RGD1562654, anticorps protein RFT1 homolog, anticorps RFT1 homolog, anticorps LOC412489, anticorps LOC100453537, anticorps RFT1, anticorps rft1, anticorps LOC100633251, anticorps LOC100651701, anticorps Rft1
    Sujet
    N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
    Alias Symbols: CDG1N
    Protein Interaction Partner: PSMA3, UBC, NEDD4,
    Protein Size: 541
    Poids moléculaire
    60 kDa
    ID gène
    91869
    NCBI Accession
    NM_052859, NP_443091
    UniProt
    Q96AA3
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