TMEM123 anticorps (C-Term)
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- Antigène Voir toutes TMEM123 Anticorps
- TMEM123 (Transmembrane Protein 123 (TMEM123))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TMEM123 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SSVTITTTMH SEAKKGSKFD TGSFVGGIVL TLGVLSILYI GCKMYYSRRG
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TMEM123. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM123
- Top Product
- Discover our top product TMEM123 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 208 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TMEM123 (Transmembrane Protein 123 (TMEM123))
- Autre désignation
- TMEM123 (TMEM123 Produits)
- Synonymes
- anticorps KCT3, anticorps PORIMIN, anticorps PORMIN, anticorps 2310075C12Rik, anticorps RGD1305625, anticorps kct3, anticorps pormin, anticorps porimin, anticorps transmembrane protein 123, anticorps transmembrane protein 123 L homeolog, anticorps TMEM123, anticorps Tmem123, anticorps tmem123.L, anticorps tmem123
- Sujet
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TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Alias Symbols: KCT3, PORIMIN, PORMIN
Protein Interaction Partner: MAGEA11, ELAVL1,
Protein Size: 208 - Poids moléculaire
- 19 kDa
- ID gène
- 114908
- NCBI Accession
- NM_052932, NP_443164
- UniProt
- Q8N131
- Pathways
- Regulation of Cell Size
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