SPOP-B anticorps (C-Term)
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- Antigène Voir toutes SPOP-B Anticorps
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPOP-B est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YHASDVLETS GWKSMVVSHP HLVAEAYRSL ASAQCPFLGP PRKRLKQS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SPOP. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SPOP
- Top Product
- Discover our top product SPOP-B Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 374 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Autre désignation
- SPOP (SPOP-B Produits)
- Synonymes
- anticorps BTBD32, anticorps TEF2, anticorps AI315626, anticorps Pcif1, anticorps zgc:64140, anticorps spop, anticorps tef2, anticorps speckle type BTB/POZ protein, anticorps speckle-type POZ protein, anticorps speckle type POZ protein S homeolog, anticorps SPOP, anticorps Spop, anticorps spop, anticorps spop.S
- Sujet
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SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Alias Symbols: TEF2
Protein Interaction Partner: CUL3, SPOP, DEK, GLI2, AR, ATM, RXRB, MYD88, DAXX, NCOA3, SRRM1, GIT2, FADD, PIAS1, UBC, UBE2E3, PIP4K2B, ESR1, BMI1, RTN3, H2AFY, DPPA2, ZBTB16, HCST, TRAF1, PDX1, DDIT3, TRAF6, SIRT2, DOK2, PIP5K1B, GDI1, KPNA6,
Protein Size: 374 - Poids moléculaire
- 42 kDa
- ID gène
- 8405
- NCBI Accession
- NM_001007226, NP_001007227
- UniProt
- O43791
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