FIP200 anticorps (C-Term)

N° du produit ABIN2784196

Détail du produit anti-FIP200 anticorps

Antigène: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIP200 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SGASRRPWVL GKVMEKEYCQ AKKAQNRFKV PLGTKFYRVK AVSWNKKV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RB1CC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1591 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FIP200

Antigène: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Autre désignation: RB1CC1 (RB1CC1 Produits)

Synonymes: anticorps DKFZp459E2330, anticorps CC1, anticorps FIP200, anticorps 2900055E04Rik, anticorps 5930404L04Rik, anticorps Cc1, anticorps LaXp180, anticorps RB1 inducible coiled-coil 1, anticorps RB1 inducible coiled-coil 1 L homeolog, anticorps RB1-inducible coiled-coil 1, anticorps RB1CC1, anticorps rb1cc1.L, anticorps rb1cc1, anticorps Rb1cc1

Sujet: RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
Alias Symbols: CC1, DRAGOU14, FIP200
Protein Interaction Partner: ATG16L1, SESN2, ATG5, UBC, EXOC1, DYRK2, PINK1, CALCOCO2, RFWD2, CTNNB1, GABARAPL1, GABARAP, VHL, RNF111, SMARCB1, SKIL, SKI, TBKBP1, TP53, ATG13, ULK2, SAFB2, ULK1, SAFB, RPA2, RPA1, PRKAB2, PRKAA2, HSBP1, MAP1LC3C, SMCR8, ATG101, YLPM1, TBK1, RBMX, PTK2
Protein Size: 1591

Poids moléculaire: 183 kDa

ID gène: 9821

NCBI Accession: NM_001083617, NP_001077086

UniProt: Q8TDY2

Pathways: Regulation of Cell Size, Autophagy