APC2 anticorps (Middle Region)

N° du produit ABIN2784219

Détail du produit anti-APC2 anticorps

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LAVARIDQLV EDISALHTSS DDSFSLSSGD PGQEAPREGR AQSCSPCRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against APC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human APC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2303 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APC2

Antigène: APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

Autre désignation: APC2 (APC2 Produits)

Synonymes: anticorps APCL, anticorps AI852447, anticorps R75424, anticorps APC2, WNT signaling pathway regulator, anticorps adenomatosis polyposis coli 2, anticorps APC2, anticorps Apc2

Sujet: APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.
Alias Symbols: APCL
Protein Interaction Partner: CTNNB1, NFX1, UBC, CDC27, ANAPC4, ANAPC10, CDC16, CDC23, ANAPC11, ANAPC7, ANAPC5, CDC26, CDH1, ANAPC1, MAPRE3, MAPRE1, Axin1, AXIN2, ACTA1,
Protein Size: 2303

Poids moléculaire: 244 kDa

ID gène: 10297

NCBI Accession: NM_005883, NP_005874

UniProt: Q9UJX6

Pathways: Signalisation WNT