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FLASH anticorps (N-Term)

CASP8AP2 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784233
  • Antigène Voir toutes FLASH (CASP8AP2) Anticorps
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Épitope
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye
    Hôte
    • 20
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FLASH est non-conjugé
    Application
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
    Top Product
    Discover our top product CASP8AP2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1982 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Pi, Lee: "Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." dans: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).

  • Antigène
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Autre désignation
    CASP8AP2 (CASP8AP2 Produits)
    Synonymes
    anticorps CASP8AP2, anticorps FLASH, anticorps fc74h10, anticorps wu:fc74h10, anticorps zgc:113449, anticorps CED-4, anticorps RIP25, anticorps AA387232, anticorps D4Ertd659e, anticorps mKIAA1315, anticorps caspase 8 associated protein 2, anticorps CASP8AP2, anticorps casp8ap2, anticorps Casp8ap2
    Sujet
    CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CED-4, FLASH, FLJ11208, KIAA1315, RIP25
    Protein Interaction Partner: ced-3, BCL2L1, PML, CTBP2, CREM, SUMO1, SUMO2, PIAS1, CASP10, TRIM21, UBC, CALM1, UBE2I, SREBF2, GLUL, SP100, CASP8AP2, FADD, TRAF2, CASP8, FAS,
    Protein Size: 1982
    Poids moléculaire
    223 kDa
    ID gène
    9994
    NCBI Accession
    NM_012115, NP_036247
    UniProt
    Q9UKL3
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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