SPRY4 anticorps (Middle Region)
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- Antigène Voir toutes SPRY4 Anticorps
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPRY4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LCYLPATGCV KLAQRGYDRL RRPGCRCKHT NSVICKAASG DAKTSRPDKP
- Homologie
- Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SPRY4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SPRY4
- Top Product
- Discover our top product SPRY4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 322 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
- Autre désignation
- SPRY4 (SPRY4 Produits)
- Synonymes
- anticorps SPRY4, anticorps LOC100218545, anticorps HH17, anticorps A030006O18Rik, anticorps sprouty4, anticorps sprouty RTK signaling antagonist 4, anticorps sprouty (Drosophila) homolog 4, anticorps sprouty homolog 4 (Drosophila), anticorps Spry4, anticorps SPRY4, anticorps spry4
- Sujet
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SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS, MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).
Alias Symbols: -
Protein Interaction Partner: GRB2, SPRY2, SPRY4, TESK1, RAF1, CBL,
Protein Size: 322 - Poids moléculaire
- 35 kDa
- ID gène
- 81848
- NCBI Accession
- NM_030964, NP_112226
- UniProt
- Q9C004
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