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URI1 anticorps (Middle Region)

URI1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784320
  • Antigène Voir toutes URI1 Anticorps
    URI1 (URI1, Prefoldin-Like Chaperone (URI1))
    Épitope
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 36
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
    Hôte
    • 34
    • 3
    Lapin
    Clonalité
    • 36
    • 1
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp URI1 est non-conjugé
    Application
    • 27
    • 16
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    NGEYVPRKSI LKSRSRENSV CSDTSESSAA EFDDRRGVLR SISCEEATCS
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 80%
    Attributs du produit
    This is a rabbit polyclonal antibody against C19orf2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human C19orf2
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 495 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    URI1 (URI1, Prefoldin-Like Chaperone (URI1))
    Autre désignation
    C19orf2 (URI1 Produits)
    Synonymes
    anticorps c19orf2, anticorps C19orf2, anticorps NNX3, anticorps PPP1R19, anticorps RMP, anticorps URI, anticorps URI1 prefoldin-like chaperone L homeolog, anticorps URI1, prefoldin like chaperone, anticorps uri1.L, anticorps URI1
    Sujet
    The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
    Protein Interaction Partner: RPAP3, UBC, ITCH, NEDD4, ATF7, TTI1, RUVBL1, RPS6KB1, PPP1CC, HSP90AA1, APP, UXT, RPAP2, GPN1, RUVBL2, STAP1, POLR2E, URI1, DMAP1, GTF2F2,
    Protein Size: 495
    Poids moléculaire
    55 kDa
    ID gène
    8725
    NCBI Accession
    NM_134447, NP_604431
    UniProt
    Q6NX55
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