DCLRE1C anticorps (N-Term)

N° du produit ABIN2784440

Cet anticorps Lapin Polyclonal détecte spécifiquement DCLRE1C dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Lapin, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour DCLRE1C anticorps (N-Term) (ABIN2784440)

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCLRE1C anticorps

Épitope: N-Term

Séquence: SSFEGQMAEY PTISIDRFDR ENLRARAYFL SHCHKDHMKG LRAPTLKRRL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DCLRE1C

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 692 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: DCLRE1C

Sujet: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
Alias Symbols: A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C
Protein Interaction Partner: XRCC5, PRKDC, RAD50, NBN, MRE11A, BRCA1, ATR, ATM, PSMD9, DDB2, DDB1, FBXW7, TP53BP1,
Protein Size: 692

Poids moléculaire: 78 kDa

ID gène: 64421

NCBI Accession: NM_001033855, NP_001029027

UniProt: Q96SD1

Pathways: Réparation de l'ADN