Frataxin anticorps (C-Term)

N° du produit ABIN2784465

Détail du produit anti-Frataxin anticorps

Antigène: Frataxin (FXN)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Cobaye, Chien, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: Western Blotting (WB)

Séquence: EFFEDLADKP YTLKDYDVSF GDGVLTIKLG GDLGTYVINK QTPNKQIWLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Rat

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 208 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: Fxn (FXN Produits)

Synonymes: anticorps zgc:158218, anticorps LOC100284365, anticorps BcDNA:AT09528, anticorps CG8971, anticorps DFH, anticorps Dfh, anticorps Dmel\\CG8971, anticorps X25, anticorps dfh, anticorps CyaY, anticorps FA, anticorps FARR, anticorps FRDA, anticorps RGD1565754, anticorps Frda, anticorps frataxin, anticorps fxn, anticorps LOC100284365, anticorps TVAG_182150, anticorps fh, anticorps FTX1, anticorps FXN, anticorps Fxn

Sujet: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1.
Alias Symbols: RGD1565754, Fxn
Protein Size: 208

Poids moléculaire: 23 kDa

ID gène: 499335

NCBI Accession: NM_001191952, XP_001078791

UniProt: D3ZYW7

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size