TNNT3 anticorps (N-Term)

N° du produit ABIN2784497

Détail du produit anti-TNNT3 anticorps

Antigène: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Cheval, Chien, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT3 est non-conjugé

Application: Western Blotting (WB)

Séquence: PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 250 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TNNT3 (ABIN2784497)

Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." dans: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." dans: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

Détails sur TNNT3

Antigène: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Autre désignation: TNNT3 (TNNT3 Produits)

Synonymes: anticorps fTnT, anticorps tnnt3a, anticorps TNTF, anticorps TnTf, anticorps Tnt, anticorps Tnnt3, anticorps troponin T3, fast skeletal type, anticorps troponin T3, skeletal, fast, anticorps troponin T3, fast skeletal type S homeolog, anticorps troponin T type 3 (skeletal, fast), anticorps troponin T1, slow skeletal type, anticorps TNNT3, anticorps Tnnt3, anticorps tnnt3.S, anticorps TNNT1

Sujet: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Alias Symbols: AMCD2B, DA2B, DKFZp779M2348, FSSV, TNTF
Protein Interaction Partner: TNNC1, TPM1, TNNI2, TNNC2, TNNT3, NUDT3, TSG101, TRIM63, SNUPN, HAP1,
Protein Size: 250

Poids moléculaire: 30 kDa

ID gène: 7140

NCBI Accession: NM_001042780, NP_001036245