HIST2H2AA3 anticorps (Middle Region)

N° du produit ABIN2784541

Détail du produit anti-HIST2H2AA3 anticorps

Antigène: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST2H2AA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHHKAKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HIST2H2AA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 130 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HIST2H2AA3

Antigène: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Autre désignation: HIST2H2AA3 (HIST2H2AA3 Produits)

Synonymes: anticorps H2A, anticorps H2A.2, anticorps H2A/O, anticorps H2A/q, anticorps H2AFO, anticorps H2a-615, anticorps HIST2H2AA, anticorps Hist2h2aa, anticorps Hist2h2aa1, anticorps histone cluster 2 H2A family member a3, anticorps histone cluster 2 H2A family member A3, anticorps HIST2H2AA3, anticorps Hist2h2aa3

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AA3 is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA
Protein Interaction Partner: USP21, DNAJC2, USP16, AURKB, UBC, WWOX, BAP1, SUZ12, RNF2, HCVgp1, PRMT6, IL33, APP, NOC2L, MEN1, SUMO2, RNF20, MSL2, BMI1, RNF168, HDAC1, PARP1, SRRM1, G3BP1, UBE2H, RCC1, TBL1X,
Protein Size: 130

Poids moléculaire: 14 kDa

ID gène: 8337

NCBI Accession: NM_003516, NP_003507

UniProt: Q7L7L0

Pathways: Telomere Maintenance