CBX2 anticorps (N-Term)
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- Antigène Voir toutes CBX2 Anticorps
- CBX2 (Chromobox Homolog 2 (CBX2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBX2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SSSSSSSTSS SSSSDEEDDS DLDAKRGPRG RETHPVPQKK AQILVAKPEL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CBX2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CBX2
- Top Product
- Discover our top product CBX2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 532 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CBX2 (Chromobox Homolog 2 (CBX2))
- Autre désignation
- CBX2 (CBX2 Produits)
- Synonymes
- anticorps cbx2, anticorps M33, anticorps pc1, anticorps wu:fd20e09, anticorps zgc:103563, anticorps MOD2, anticorps pc, anticorps CDCA6, anticorps SRXY5, anticorps cdca6, anticorps m33, anticorps chromobox 2, anticorps chromobox homolog 2 (Drosophila Pc class), anticorps chromobox 2 L homeolog, anticorps cbx2, anticorps CBX2, anticorps Cbx2, anticorps cbx2.L
- Sujet
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CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: CDCA6, M33, MGC10561, SRXY5
Protein Interaction Partner: KRTAP10-3, KRTAP10-1, KRTAP10-9, KRTAP10-7, RBMY1F, DHX57, KRTAP2-4, RBMY1A1, RNF2, BMI1, MDFI, SOX2, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK2A1, CENPE, PARP1, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK
Protein Size: 532 - Poids moléculaire
- 56 kDa
- ID gène
- 84733
- NCBI Accession
- NM_005189, NP_005180
- UniProt
- Q14781
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