MBNL2 anticorps (Middle Region)

N° du produit ABIN2784554

Détail du produit anti-MBNL2 anticorps

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBNL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MBNL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 255 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MBNL2

Antigène: MBNL2 (Muscleblind-Like 2 (MBNL2))

Autre désignation: MBNL2 (MBNL2 Produits)

Synonymes: anticorps 1110002M11Rik, anticorps AI047808, anticorps AI837313, anticorps AI849185, anticorps AL118326, anticorps MBLL, anticorps R75232, anticorps mKIAA4072, anticorps wu:fj89c04, anticorps MBLL39, anticorps PRO2032, anticorps muscleblind like splicing factor 2, anticorps muscleblind-like splicing regulator 2, anticorps muscleblind like splicing regulator 2, anticorps Mbnl2, anticorps mbnl2, anticorps MBNL2

Sujet: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
Alias Symbols: DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
Protein Interaction Partner: BMI1, ELAVL1, UBC,
Protein Size: 255

Poids moléculaire: 28 kDa

ID gène: 10150

NCBI Accession: NM_005757, NP_005748

UniProt: O95205