PAXIP1 anticorps (N-Term)
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- Antigène Voir toutes PAXIP1 Anticorps
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAXIP1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MFDDSSDSSP EKQERNLNWT PAEVPQLAAA KRRLPQGKEP GLINLCANVP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against PAXIP1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
- Top Product
- Discover our top product PAXIP1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 697 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
- Autre désignation
- PAXIP1 (PAXIP1 Produits)
- Synonymes
- anticorps CAGF29, anticorps PACIP1, anticorps PAXIP1L, anticorps PTIP, anticorps TNRC2, anticorps wu:fa04b06, anticorps zgc:92593, anticorps cagf28, anticorps cagf29, anticorps k14, anticorps pacip1, anticorps paxip1l, anticorps ptip, anticorps tnrc2, anticorps D5Ertd149e, anticorps PAX interacting protein 1, anticorps PAX interacting (with transcription-activation domain) protein 1, anticorps PAX interacting protein 1 L homeolog, anticorps PAXIP1, anticorps paxip1, anticorps paxip1.L, anticorps Paxip1
- Sujet
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PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Alias Symbols: PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L, FLJ41049
Protein Interaction Partner: MAPRE2, POM121, NXT1, PPARG, XAGE1E, SMAD2, SPATA18, COMTD1, BTBD16, DIS3L, LACTB, HNRNPLL, ZNF251, ZNF622, BTBD6, C7orf50, FAM175A, TMEM120A, FAHD1, TM2D3, ATHL1, CENPU, DYNC2H1, BRCC3, KRI1, ANAPC1, NOM1, POLR1E, NCAPG, AASDHPPT, RBM25, CATSPERG, WDR48,
Protein Size: 697 - Poids moléculaire
- 74 kDa
- ID gène
- 22976
- NCBI Accession
- NM_007349
- UniProt
- Q6ZW49
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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