PACS2 anticorps (Middle Region)
-
- Antigène Voir toutes PACS2 Anticorps
- PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
-
Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PACS2 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- AHQLPIAEAM LTYKQKSPDE ESSQKFIPFV GVVKVGIVEP SSATSGDSDD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against PACS2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PACS2
- Top Product
- Discover our top product PACS2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 889 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
- Autre désignation
- PACS2 (PACS2 Produits)
- Synonymes
- anticorps PACS-2, anticorps PACS1L, anticorps 6720425G15Rik, anticorps AW208651, anticorps AW489976, anticorps E230011J22, anticorps Pacs1l, anticorps mKIAA0602, anticorps phosphofurin acidic cluster sorting protein 2, anticorps PACS2, anticorps Pacs2
- Sujet
-
PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Alias Symbols: FLJ25488, KIAA0602, PACS1L, PACS-2
Protein Interaction Partner: UBC, TRAF2, BIRC3, BIRC2, PKD2, BID,
Protein Size: 889 - Poids moléculaire
- 98 kDa
- ID gène
- 23241
- NCBI Accession
- NM_015197, NP_056012
- UniProt
- Q86VP3
-