Endonuclease G anticorps (Middle Region)

N° du produit ABIN2784751

Détail du produit anti-Endonuclease G anticorps

Antigène: Endonuclease G (ENDOG)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endonuclease G est non-conjugé

Application: Western Blotting (WB)

Séquence: YVMPNAPVDE AIPLERFLVP IESIERASGL LFVPNILARA GSLKAITAGS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ENDOG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ENDOG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 297 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Endonuclease G (ABIN2784751)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Détails sur Endonuclease G

Antigène: Endonuclease G (ENDOG)

Autre désignation: ENDOG (ENDOG Produits)

Synonymes: anticorps CG8862, anticorps Dmel\\CG8862, anticorps Tb08.10J17.140, anticorps Tb08.10J17.90, anticorps TBC1D13, anticorps endog, anticorps ENDOG, anticorps wu:fb79c08, anticorps zgc:110020, anticorps Endonuclease G, anticorps endonuclease G, anticorps putative endonuclease G, anticorps endonuclease G, mitochondrial, anticorps endonuclease G L homeolog, anticorps EndoG, anticorps Tc00.1047053506867.10, anticorps Tb927.8.4040, anticorps Tb927.8.4090, anticorps LBRM_10_0750, anticorps LMJF_10_0610, anticorps NAEGRDRAFT_78507, anticorps ENDOG, anticorps endog, anticorps eNDOG, anticorps LOC100529218, anticorps Endog, anticorps endog.L

Sujet: ENDOG cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, ENDOG also has ribonuclease (RNase) and RNase H activities. ENDOG is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Alias Symbols: FLJ27463
Protein Interaction Partner: UBC, BIRC2, DNAJA4, STUB1, HSPA4, AIFM1, FEN1,
Protein Size: 297

Poids moléculaire: 28 kDa

ID gène: 2021

NCBI Accession: NM_004435, NP_004426

UniProt: Q14249

Pathways: Apoptose