ACTR1B anticorps (C-Term)

N° du produit ABIN2784773

Détail du produit anti-ACTR1B anticorps

Antigène: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTR1B est non-conjugé

Application: Western Blotting (WB)

Séquence: KIKISAPQER LYSTWIGGSI LASLDTFKKM WVSKKEYEED GSRAIHRKTF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ACTR1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ACTR1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 376 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACTR1B (ABIN2784773)

Hwang, Weng, Lin, Bau, Ko, Tsai, Tsai, Wu, Lin, Huang, Kuo: "Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart." dans: Molecular and cellular biochemistry, Vol. 311, Issue 1-2, pp. 179-87, (2008) (PubMed).

Détails sur ACTR1B

Antigène: ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))

Autre désignation: ACTR1B (ACTR1B Produits)

Synonymes: anticorps ARP1B, anticorps CTRN2, anticorps PC3, anticorps 2310066K23Rik, anticorps AA960180, anticorps AI851923, anticorps Arp1b, anticorps ACTR1B, anticorps ARP1 actin related protein 1 homolog B, anticorps ARP1 actin-related protein 1B, centractin beta, anticorps ARP1 actin-related protein 1 homolog B, anticorps ARP1 actin-related protein 1 homolog B, centractin beta (yeast), anticorps beta-centractin, anticorps ACTR1B, anticorps Actr1b, anticorps LOC100594459

Sujet: ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.
Alias Symbols: ARP1B, CTRN2, PC3
Protein Interaction Partner: SEH1L, ACTR10, DCTN4, DCTN2, ACTR1A, RABEP1, LMNB1, DCTN3, APP, SMAD6, CUL3, UBC, TK1, MAPK6, CSNK2B, Dctn1, Capza1, CHD3, ACTA1,
Protein Size: 376

Poids moléculaire: 42 kDa

ID gène: 10120

NCBI Accession: NM_005735, NP_005726

UniProt: P42025