RALBP1 anticorps (N-Term)
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- Antigène Voir toutes RALBP1 Anticorps
- RALBP1 (RalA Binding Protein 1 (RALBP1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Porc, Lapin, Boeuf (Vache), Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RALBP1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP
- Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RALBP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1
- Top Product
- Discover our top product RALBP1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 655 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RALBP1 (RalA Binding Protein 1 (RALBP1))
- Autre désignation
- RALBP1 (RALBP1 Produits)
- Synonymes
- anticorps rip1, anticorps rlip1, anticorps rlip-A, anticorps rlip76, anticorps RALBP1, anticorps RLIP76, anticorps Rip1, anticorps RIP1, anticorps RLIP1, anticorps ralA binding protein 1 S homeolog, anticorps ralA binding protein 1, anticorps ralbp1.S, anticorps RALBP1, anticorps ralbp1, anticorps Ralbp1
- Sujet
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RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Alias Symbols: RIP, RIP1, RLIP76, RLIP1
Protein Interaction Partner: TNIP1, CEP57, SMARCE1, PPL, GPS2, GSE1, ZNF707, ZBTB38, C1orf216, TBRG1, AMOTL2, TFPT, UBC, RALB, GPSM1, PRKCA, CPSF2, POLR2A, AP2A1, SYNJ2BP, HOOK2, REPS1, FADD, RAC1, TRAF2, CASP8, AP2M1, REPS2, IKBKG, RALA, CCNB1, HSP90AA1, HSF1, EPN1, NUMB, GTF3A, TNF
Protein Size: 655 - Poids moléculaire
- 76 kDa
- ID gène
- 10928
- NCBI Accession
- NM_006788, NP_006779
- UniProt
- Q15311
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