CRY2 anticorps (N-Term)

N° du produit ABIN2784909

Détail du produit anti-CRY2 anticorps

Antigène: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRY2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IELNGQKPPL TYKRFQAIIS RMELPKKPVG LVTSQQMESC RAEIQENHDE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CRY2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CRY2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 593 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CRY2 (ABIN2784909)

Currie, Doherty, Sillar: "Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. 6053-8, (2016) (PubMed).

Détails sur CRY2

Antigène: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Autre désignation: CRY2 (CRY2 Produits)

Synonymes: anticorps Cry2, anticorps Cry, anticorps GB10211, anticorps CRY2, anticorps AT-PHH1, anticorps ATCRY2, anticorps CRYPTOCHROME 2 APOPROTEIN, anticorps F19P19.14, anticorps F19P19_14, anticorps FHA, anticorps PHH1, anticorps cryptochrome 2, anticorps HCRY2, anticorps PHLL2, anticorps AV006279, anticorps D130054K12Rik, anticorps gCry2, anticorps cryptochrome circadian regulator 2, anticorps cryptochrome 2, anticorps cryptochrome Cry2, anticorps cryptochrome circadian clock 2, anticorps cryptochrome 2 (photolyase-like), anticorps CRY2, anticorps Cry2, anticorps cry2, anticorps LOC100502533

Sujet: CRY2 is a blue light-dependent regulator of the circadian feedback loop.CRY2 inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. CRY2 acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity.CRY2 has no photolyase activity. CRY2 is capable of translocating circadian clock core proteins such as PER proteins to the nucleus.CRY2 may inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
Alias Symbols: FLJ10332, HCRY2, KIAA0658, PHLL2
Protein Interaction Partner: MTUS2, PDE9A, CTBP1, UBC, FBXL3, FBXL21, BTRC, CUL1, SKP1, ATXN1, Csnk1e, PER3, PER2, PER1, PPP5C, TTC1, CRY2, TIMELESS,
Protein Size: 593

Poids moléculaire: 67 kDa

ID gène: 1408

NCBI Accession: NM_021117, NP_066940

UniProt: Q49AN0

Pathways: Response to Water Deprivation, Protein targeting to Nucleus