FBXW10 anticorps (Middle Region)

N° du produit ABIN2784922

Détail du produit anti-FBXW10 anticorps

Antigène: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW10 est non-conjugé

Application: Western Blotting (WB)

Séquence: RKIHLLDIIQ VKAIPVEFRG HAGSVRALFL CEEENFLLSG SYDLSIRYWD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXW10

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1051 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXW10

Antigène: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Autre désignation: FBXW10 (FBXW10 Produits)

Synonymes: anticorps Fbw10, anticorps HREP, anticorps SM25H2, anticorps SM2SH2, anticorps CMT1A duplicated region transcript 1, anticorps F-box and WD repeat domain containing 10, anticorps tripartite motif containing 16, anticorps F-box and WD-40 domain protein 10, anticorps CDRT1, anticorps FBXW10, anticorps Fbxw10, anticorps Cdrt1, anticorps TRIM16

Sujet: Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbw10, HREP, SM25H2, SM2SH2
Protein Interaction Partner: CUL5,
Protein Size: 1051

Poids moléculaire: 120 kDa

ID gène: 10517

NCBI Accession: NM_031456, NP_113644

UniProt: Q5XX13