TSEN15 anticorps (C-Term)

N° du produit ABIN2784943

Détail du produit anti-TSEN15 anticorps

Antigène: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN15 est non-conjugé

Application: Western Blotting (WB)

Séquence: ASLSHNRIRE ILKASRKLQG DPELPMSFTL AIVESDSTIV YYKLTDGFML

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Tsen15. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 168 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TSEN15

Antigène: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Autre désignation: Tsen15 (TSEN15 Produits)

Synonymes: anticorps 5730449L18Rik, anticorps AL023077, anticorps Sen15, anticorps C1orf19, anticorps sen15, anticorps tRNA splicing endonuclease subunit 15, anticorps Tsen15, anticorps TSEN15

Sujet: Tsen15 is a non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Alias Symbols: 5730449L18Rik, AL023077, Sen15
Protein Interaction Partner: Eed,
Protein Size: 168

Poids moléculaire: 18 kDa

ID gène: 66637

NCBI Accession: NM_025677, NP_079953

UniProt: Q8R3W5